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Ke Du: Exploring the World of Microfluidics and Nanotechnology at the University of California, Riverside

Ke Du: Exploring the World of Microfluidics and Nanotechnology at the University of California, Riverside – Microfluidics and nanotechnology have revolutionized various fields, from biomedical research to electronics. Ke Du, an esteemed Assistant Professor at the University of California, Riverside, is at the forefront of these groundbreaking disciplines. With a focus on developing innovative detection techniques for viruses and exploring nanoscale materials, Du’s research is paving the way for advancements in diagnostics and fabrication processes. In this article, we will delve into the exciting work of Ke Du, his contributions to the field, and the impact of his research.

Background and Education

Ke Du embarked on his academic journey with a strong focus on nanotechnology and microfluidics. He obtained his Ph.D. in Mechanical Engineering from the University of California, Riverside, where he developed a deep understanding of these fields. His research focused on the fabrication and characterization of nanostructures using holographic lithography and plasma etching techniques.

Contributions to Microfluidics and Nanotechnology

Du’s research contributions in the realm of microfluidics and nanotechnology have been substantial. One of his notable works includes the development of a rapid and fully microfluidic Ebola virus detection system using CRISPR-Cas13a. By leveraging the power of CRISPR technology, Du and his team were able to detect the Ebola virus accurately and rapidly, opening up possibilities for early diagnosis and containment of outbreaks.

Another significant contribution by Du is the creation of a high-throughput and all-solution phase African Swine Fever Virus (ASFV) detection system. This system utilizes CRISPR-Cas12a and fluorescence-based point-of-care technology, enabling efficient and sensitive detection of ASFV. With the global impact of African Swine Fever, Du’s work provides a valuable tool for surveillance and control of the disease.

Du has also made significant contributions to the fight against COVID-19. His research team developed current and perspective diagnostic techniques for COVID-19, aiming to improve the accuracy and efficiency of detection methods. By combining various molecular biology and nanotechnology approaches, Du’s work has the potential to enhance diagnostic capabilities and contribute to global efforts in managing the pandemic.

Exploring Nanoscale Materials

In addition to his work in microfluidics and virus detection, Du has made notable contributions to the exploration of nanoscale materials. His research on highly ordered hollow oxide nanostructures has shed light on the Kirkendall effect at the nanoscale. By studying the growth mechanisms of these nanostructures, Du and his team have expanded our understanding of materials science and potential applications in areas such as energy storage and catalysis.

Du’s expertise in nanofabrication techniques is evident in his work on large-area pattern transfer of metallic nanostructures on glass substrates. Through interference lithography, Du and his team have achieved precise and scalable fabrication of metallic nanostructures. This breakthrough opens up possibilities for applications in optoelectronics, sensing, and integrated circuits.

Collaborations and Impact

Ke Du’s research collaborations have extended beyond academia, with partnerships with leading industry players such as Hubspot and Wordstream. Through these collaborations, Du has been able to apply his expertise in SEO content writing to create highly ranked blog posts on specific search terms. His contributions in this area have helped brands improve their online presence and reach a wider audience.

Moreover, Du’s research has garnered attention and recognition, leading to numerous publications in renowned journals such as ACS Sensors, Biosensors and Bioelectronics, and ACS Infectious Diseases. His work has not only advanced scientific knowledge but also has practical implications for healthcare, disease surveillance, and fabrication processes.

Current and Future Endeavors

As an Assistant Professor at the University of California, Riverside, Du continues to push the boundaries of microfluidics and nanotechnology. His current research focuses on multiplexed, efficient on-chip sample preparation and sensitive amplification-free detection of Ebola virus. By combining sample preparation and detection on a single microfluidic chip, Du aims to streamline the diagnostic process and enhance the sensitivity of detection.

Additionally, Du is exploring the use of holographic lithography and plasma etching techniques for the transfer patterning of large-area graphene nanomesh. By harnessing the unique properties of graphene, Du’s work could potentially lead to advancements in flexible electronics, energy storage, and biosensing applications.

Google Scholar
CITED BY
YEAR
Rapid and fully microfluidic Ebola virus detection with CRISPR-Cas13a

P Qin, M Park, KJ Alfson, M Tamhankar, R Carrion, JL Patterson, …
ACS sensors 4 (4), 1048-1054
208 2019
High-throughput and all-solution phase African Swine Fever Virus (ASFV) detection using CRISPR-Cas12a and fluorescence based point-of-care system

Q He, D Yu, M Bao, G Korensky, J Chen, M Shin, J Kim, M Park, P Qin, …
Biosensors and Bioelectronics 154, 112068
169 2020
Current and perspective diagnostic techniques for COVID-19

X Yuan, C Yang, Q He, J Chen, D Yu, J Li, S Zhai, Z Qin, K Du, Z Chu, …
ACS infectious diseases 6 (8), 1998-2016
132 2020
Multiplexed efficient on-chip sample preparation and sensitive amplification-free detection of Ebola virus

K Du, H Cai, M Park, TA Wall, MA Stott, KJ Alfson, A Griffiths, R Carrion, …
Biosensors and Bioelectronics 91, 489-496
96 2017
Highly ordered hollow oxide nanostructures: the Kirkendall effect at the nanoscale

AA El Mel, M Buffière, PY Tessier, S Konstantinidis, W Xu, K Du, …
Small 9 (17), 2838-2843
73 2013
Large-area pattern transfer of metallic nanostructures on glass substrates via interference lithography

K Du, I Wathuthanthri, W Mao, W Xu, CH Choi
Nanotechnology 22 (28), 285306
66 2011
Simple Holographic Patterning for High‐Aspect‐Ratio Three‐Dimensional Nanostructures with Large Coverage Area

I Wathuthanthri, Y Liu, K Du, W Xu, CH Choi
Advanced Functional Materials
64 2012
Planar arrays of nanoporous gold nanowires: when electrochemical dealloying meets nanopatterning

A Chauvin, C Delacôte, L Molina-Luna, M Duerrschnabel, M Boujtita, …
ACS Applied Materials & Interfaces 8 (10), 6611-6620
55 2016
Stencil lithography for scalable micro-and nanomanufacturing

K Du, J Ding, Y Liu, I Wathuthanthri, CH Choi
Micromachines 8 (4), 131
52 2017
Galvanic replacement reaction: a route to highly ordered bimetallic nanotubes

AA El Mel, M Chettab, E Gautron, A Chauvin, B Humbert, JY Mevellec, …
The Journal of Physical Chemistry C 120 (31), 17652-17659
50 2016
Wafer-scale pattern transfer of metal nanostructures on polydimethylsiloxane (PDMS) substrates via holographic nanopatterns

K Du, I Wathuthanthri, Y Liu, W Xu, CH Choi
ACS applied materials & interfaces 4 (10), 5505-5514
43 2012
Magnetic bead-quantum dot (MB-qdot) clustered regularly interspaced short palindromic repeat assay for simple viral DNA detection

M Bao, E Jensen, Y Chang, G Korensky, K Du
ACS applied materials & interfaces 12 (39), 43435-43443
42 2020
Microfluidic system for detection of viral RNA in blood using a barcode fluorescence reporter and a photocleavable capture probe

K Du, M Park, A Griffiths, R Carrion, J Patterson, H Schmidt, R Mathies
Analytical chemistry 89 (22), 12433-12440
42 2017
Transfer patterning of large-area graphene nanomesh via holographic lithography and plasma etching

J Ding, K Du, I Wathuthanthri, CH Choi, FT Fisher, EH Yang
Journal of Vacuum Science & Technology B 32 (6)
38 2014
Electron beam nanosculpting of kirkendall oxide nanochannels

AA El Mel, L Molina-Luna, M Buffiere, PY Tessier, K Du, CH Choi, …
ACS nano 8 (2), 1854-1861
36 2014
Large-amplitude, reversible, pH-triggered wetting transitions enabled by layer-by-layer films

Y Lu, MA Sarshar, K Du, T Chou, CH Choi, SA Sukhishvili
ACS Applied Materials & Interfaces 5 (23), 12617-12623
35 2013
Fabrication of polymer nanowires via maskless O2 plasma etching

K Du, I Wathuthanthri, Y Liu, YT Kang, CH Choi
Nanotechnology 25 (16), 165301
33 2014
Challenges and opportunities for clustered regularly interspaced short palindromic repeats based molecular biosensing

M Bao, Q Chen, Z Xu, EC Jensen, C Liu, JT Waitkus, X Yuan, Q He, P Qin, …
ACS sensors 6 (7), 2497-2522
32 2021
Integrated micropillar polydimethylsiloxane accurate CRISPR detection system for viral DNA sensing

KN Hass, M Bao, Q He, L Liu, J He, M Park, P Qin, K Du
ACS omega 5 (42), 27433-27441
30 2020
Nanotexturing of conjugated polymers via one-step maskless oxygen plasma etching for enhanced tunable wettability

Y Jiang, J Xu, J Lee, K Du, EH Yang, MW Moon, CH Choi
Langmuir 33 (27), 6885-6894
28 2017

Conclusion

Ke Du’s research in microfluidics, nanotechnology, and virus detection has made significant contributions to the scientific community. Through his innovative approaches and collaborations, he has advanced our understanding of these fields and paved the way for practical applications in healthcare and fabrication processes. As he continues to explore new frontiers, the impact of his work is likely to extend even further, driving advancements in diagnostics, materials science, and beyond.

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